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Availability: In stock

(Gly²¹)-Amyloid β-Protein (1-40) trifluoroacetate salt

4039927

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4039927.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 158.00
CHF 146.94 (7%)
4039927.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 262.00
CHF 243.66 (7%)
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Details

Contrary to β-amyloid peptides mutated at position 22 (Dutch, Italian, Arctic mutants) the Flemish mutation (A21G) shows a decreased tendency to aggregate and a reduced neurotoxicity. In the studies of Betts and Tsubuki, A21G was degraded significantly more slowly by neprilysin than the wild-type Aβ 1-40 and the E22 mutants. The relative resistance to proteolytic degradation may account for the pathogenicity of the Aβ mutant.
Catalog Number H-6702
APC Number 62-0-61
One Letter Code DAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVV
Synonyms Amyloid β-Protein (1-40) Flemish Mutation, Amyloid β-Protein (1-40) A21G, [Gly21] β-Amyloid (1-40)
Molecular Formula C₁₉₃H₂₉₃N₅₃O₅₈S
Relative Molecular Mass 4315.84
CAS Registry Number [154362-03-5] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease