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(7-Diethylaminocoumarin-3-yl)carbonyl-Amyloid β-Protein (1-40) trifluoroacetate salt
(7-Diethylaminocoumarin-3-yl)carbonyl-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH trifluoroacetate salt

4048251

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4048251.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 199.00
CHF 185.07 (7%)
4048251.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 368.00
CHF 342.24 (7%)
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Details

Amyloid β-protein (1-40) that is N-terminally modified with the fluorescent dye (7-diethylaminocoumarin-3-yl)carbonyl (DAC or DEAC). This derivative can be utilized to assess the binding properties of amyloid β-protein (1-40) for various membranes since it behaves very similar to the native peptide. In aqueous environments the fluorophore is almost non-fluorescent whereas binding to membranes results in an increase in fluorescence intensity (λex = 430 nm, λem = 470 nm). Increases in the GM1 ganglioside and cholesterol content in the lipid bilayers facilitated the binding of this peptide. For phosphatidylcholine and phosphatidylserine no affinity was observed.
Catalog Number H-6468
Synonyms DAC-Amyloid β-Protein (1-40)
Molecular Formula C₂₀₈H₃₀₈N₅₄O₆₁S
Relative Molecular Mass 4573.13
CAS Registry Number [1802087-66-6] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease