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Availability: In stock

L-685,458 trifluoroacetate salt

4034722

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4034722.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 405.00
CHF 376.65 (7%)
4034722.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,472.00
CHF 1,368.96 (7%)
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Details

L-685458, Boc-F-psi[CHOH-CH₂]-FFLF-NH₂, a potent γ-secretase inhibitor contains a hydroxyethylene equivalent of the Phe-Phe motif. The hydroxymethylene isostere may act as a transition analog to direct the inhibitor to the active site of an aspartyl protease target. L-685458 has been used to prepare photoaffinity probes that label the active site of γ-secretase.
Catalog Number H-5106
Molecular Formula C₃₉H₅₂N₄O₆
Relative Molecular Mass 672.87
CAS Registry Number [292632-98-5] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease

4034722

Enzyme Substrates Inhibitors
γ-Secretase