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Phenylacetyl-(D-Arg²·²⁸,p-chloro-Phe⁶,Homoarg⁹·²⁹,Tyr(Me)¹⁰,Abu¹⁵,Nle²⁷)-GRF (1-29) amide (human)

4034002

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4034002.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 830.00
CHF 771.90 (7%)
4034002.1000 1 mg Ships within 3-5 business days  
CHF 1,492.00
CHF 1,387.56 (7%)
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Details

JV-1-38 exhibited antagonistic activity against human growth hormone-releasing hormone (hGH-RH) slightly less potent than JV-1-36 (H-4884) both in vitro and in vivo but proved to be very long-acting in vivo, suppressing the GH-RH induced GH release even after 60 min. Antagonists of this structure are possible candidates for clinical application in the treatment of cancers dependent on insulin-like growth factors I and II.
Catalog Number H-4886
Synonyms JV-1-38, Phenylacetyl-(D-Arg²·²⁸,p-chloro-Phe⁶,Homoarg⁹·²⁹,Tyr(Me)¹⁰,Abu¹⁵,Nle²⁷)-Sermorelin
Molecular Formula C₁₇₂H₂₈₄ClN₅₃O₄₁
Relative Molecular Mass 3785.93
CAS Registry Number [221377-79-3]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Cancer Research
Growth Factors