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Availability: In stock

H-His-Cys-Lys-Phe-Trp-Trp-OH

4026848

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4026848.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 126.00
CHF 117.18 (7%)
4026848.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 504.00
CHF 468.72 (7%)
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Details

HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3'processing and integration with an IC₅₀ of 2 µM. The peptide is also active on IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus and Moloney murine leukemia virus. It was also found to inhibit the disintegration reaction, suggesting that this hexapeptide acts at or near the catalytic site of IN.
Catalog Number H-3524
One Letter Code HCKFWW
Molecular Formula C₄₆H₅₅N₁₁O₇S
Relative Molecular Mass 906.08
CAS Registry Number [172546-75-7]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords HIV integrase inhibitor
Areas of Interest Infectious Disease
Virology

4026848

Enzyme Substrates Inhibitors
HIV Integrase