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Availability: In stock

CRF (6-33) (human, rat)
H-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-OH

4026679

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4026679.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 105.00
CHF 97.65 (7%)
4026679.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 185.00
CHF 172.05 (7%)
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Details

This CRF fragment may have two different beneficial effects in Alzheimer's disease (AD). First CRF (6-33) dissociates CRF from the CRF-binding protein and may therefore be able to restore the dramatic reduction of free CRF content in AD. Second this fragment shows cognition-enhancing properties in animal models of learning and memory, without the characteristic anxiogenic effects of CRF receptor agonists, and may therefore be useful in the treatment of memory deficits seen in AD.
Catalog Number H-3456
One Letter Code ISLDLTFHLLREVLEMARAEQLAQQAHS
Molecular Formula C₁₄₁H₂₃₁N₄₁O₄₃S
Relative Molecular Mass 3220.70
CAS Registry Number [120066-38-8]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Cognition-enhancing corticorelin fragment
Areas of Interest Alzheimer's Disease