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Acetyl-(D-Lys²,Sar³)-Melanotropin-Potentiating Factor acetate salt
Ac-Lys-D-Lys-Sar-Glu-OH acetate salt

4026111

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4026111.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 473.00
CHF 439.89 (7%)
4026111.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,891.00
CHF 1,758.63 (7%)
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Details

This metabolically stable analog of MPF is known as a neurotrophic peptide capable of CNS regeneration. It has been shown to reduce parkinsonian-like behaviour in rats with unilateral lesions of their nigro-striatal pathways. This effect is related to reversal of the mitochondrial damage to the neurons. As a mitochondrial defect is supposed to be the initial step in the genesis of Parkinson's disease, the peptide may be a very useful tool in the investigation of this disease.
Catalog Number H-2512
Synonyms Acetyl-(D-Lys⁸⁹,Sar⁹⁰)-β-Lipotropin (88-91) (human), Acetyl-(D-Lys²⁹,Sar³⁰)-β-Endorphin (28-31) (human)
Molecular Formula C₂₂H₄₀N₆O₈
Relative Molecular Mass 516.60
CAS Registry Number [81483-91-2] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Neurotrophic peptide
Areas of Interest Parkinson’s Disease

Product citations

J.S.Morley et al., Neuropeptides, 2, 109 (1981)