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Details
This peptide is a specifically designed negative control in studies with Abeta42. It is "scrambled", which means it contains the same amino acids as Abeta42, but in different order. Referring to studies by Yamin and coworkers, Teplow's Amyloid β-Protein (1-42) does not show a number of phenomena regularly observed with Abeta42 (fibril formation, oligomerization, toxicity to neurons) and furthermore has a relatively flat hydropathy profile, which can be an advantage in several studies, for example in order to avoid unspecific interaction with the cell membrane.
Catalog Number
H-8282
One Letter Code
YHAGVDKEVVFDEGAGAEHGLAQKIVRGFGVSDVSMIHINLF
Synonyms
Aβ42 scrambled II, β-Amyloid (1-42) (scrambled II)
Molecular Formula
C₂₀₃H₃₁₁N₅₅O₆₀S
Relative Molecular Mass
4514.10
CAS Registry Number
1987844-92-7
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Alzheimer's Disease
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