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Details
This peptide is a specifically designed negative control in studies with Abeta40. It is "scrambled", which means it contains the same amino acids as Abeta40, but in different order. Referring to studies by Yamin and coworkers, Teplow's Amyloid β-Protein (1-40) does not show a number of phenomena regularly observed with Abeta40 (fibril formation, oligomerization, toxicity to neurons) and furthermore has a relatively flat hydropathy profile, which can be an advantage in several studies, for example in order to avoid unspecific interaction with the cell membrane.
Catalog Number
H-8278
One Letter Code
YHAGVDKEVVFDEGGAEHGLAQKIVRGFGVSDVSMIHNLF
Synonyms
Aβ42 scrambled II, β-Amyloid (1-40) (scrambled II)
Molecular Formula
C₁₉₄H₂₉₅N₅₃O₅₈S
Relative Molecular Mass
4329.86
CAS Registry Number
1987844-71-2
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Alzheimer's Disease
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