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Defensin 5 (human) trifluoroacetate salt
H-Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg-OH trifluoroacetate salt
(Disulfide bonds, air oxidized)

4102158

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4102158.0100 0.1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 290.00
CHF 269.70 (7%)
4102158.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 950.00
CHF 883.50 (7%)
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Details

Human defensin-5 (HD 5) is a key regulator of gut microbiota homeostasis. HD 5 exhibits microbicidal activity against bacteria, fungi, and viruses and is released by Paneth cells in the small intestine.
Reduction or absence of HD 5 release in the intestinal mucosa has been associated with susceptibility to enteric pathogens, changes in composition of the microbiota, and disruption of intestinal immune homeostasis.
As a biomarker, HD 5 might be used to distinguish between ulcerative colitis (low levels of HD 5) or Crohn's colitis (high levels of HD 5).
Catalog Number H-8252
One Letter Code ATCYCRTGRCATRESLSGVCEISGRLYRLCCR
Synonyms Defensin HD 5, HD 5, Human α-defensin 5, α-Defensin 5 (human)
Molecular Formula C₁₄₄H₂₃₈N₅₀O₄₅S₆
Relative Molecular Mass 3582.18
Source Synthetic
Storage Conditions -20 ± 5 °C