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Details
FK-13, core sequence of LL-37, is protected from bacterial proteolysis by actin. FK-13 showed activity against HIV-1, EC₅₀ 3.4 μM. As removal of the N-terminal phenylalanine leads to inactivation, FKRIVQRIKDFLR corresponds to the minimal anti-HIV region of human LL-37.
Catalog Number
H-7868
One Letter Code
FKRIVQRIKDFLR
Synonyms
LL-37 (17-29), Cationic Antimicrobial Protein 18 (150-162) (human), hCAP18 (150-162) AND LL17 - 29
Molecular Formula
C₈₀H₁₃₅N₂₅O₁₇
Relative Molecular Mass
1719.11
CAS Registry Number
[717919-68-1] net
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Antimicrobial & Antiviral Peptides
Infectious Disease
Virology
Infectious Disease
Virology
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