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4092130

Availability: In stock

Orexin A (17-33) trifluoroacetate salt
H-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH₂ trifluoroacetate salt

4092130

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4092130.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
4092130.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 351.00
CHF 326.43 (7%)

Details

Orexin A (17-33) acts as selective OX1 antagonist. Truncation studies have led to OXA (17-33) as the shortest active peptide known to date with a 23-fold selectivity for OX1 over OX2. The native orexins A and B do not show distinct receptor selectivity. Both OX receptors are involved in energy homeostasis and the sleep/wake cycle, hence selective as well as dual antagonists are required for research.
Catalog Number H-7526
One Letter Code YELLHGAGNHAAGILTL
Synonyms Hypocretin-1 (17-33)
Molecular Formula C₇₉H₁₂₅N₂₃O₂₂
Relative Molecular Mass 1749.00
CAS Registry Number 343268-91-7
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Obesity Research
Links / Documents:

Product citations

N.A.German et al., ACS Med. Chem. Lett., 4, 1224 (2013)
J.G.Darker et al., Bioorg. Med. Chem. Lett., 11, 737 (2001)