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4078801

Availability: In stock

Calcium-Like Peptide 3 trifluoroacetate salt
H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH trifluoroacetate salt

4078801

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4078801.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 189.00
CHF 175.77 (7%)

Details

CALP-3, VKFGVGFK, acts as a calmodulin agonist. The octapeptide interacts with the calmodulin EF-hand motif, the Ca²⁺-binding site. CALP-3 activates phosphodiesterase in the absence of calcium and inhibits Ca²⁺-mediated cytotoxicity and apoptosis. CALP-3 is more active than CALP-1. By preventing trypsin activation within pancreatiic acinar cells CALP-3 shows potential therapeutic potential in the treatment of pancreatitis.
Catalog Number H-7344
One Letter Code VKFGVGFK
Synonyms CALP-3
Molecular Formula C₄₄H₆₈N₁₀O₉
Relative Molecular Mass 881.09
CAS Registry Number 261969-05-5
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Calmodulin agonist
Application Apoptosis & Necrosis
Gastrointestinal Research
Links / Documents:

Product citations

R.Ten Broeke et al., Eur. J. Pharmacol., 476, 151 (2003)
R.Ten Broeke et al., FASEB J., 15, 1831 (2001)
M.K.Manion et al., FASEB J., 14, 1297 (2000)
M.Villain et al., J. Biol. Chem., 275, 2676 (2000)