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4074448

Availability: Out of stock

APL1β28 trifluoroacetate salt
H-Asp-Glu-Leu-Ala-Pro-Ala-Gly-Thr-Gly-Val-Ser-Arg-Glu-Ala-Val-Ser-Gly-Leu-Leu-Ile-Met-Gly-Ala-Gly-Gly-Gly-Ser-Leu-OH trifluoroacetate salt

4074448

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price
4074448.0500 0.5 mg Request lead time  
CHF 140.00
CHF 130.20 (7%)
4074448.1000 1 mg Request lead time  
CHF 230.00
CHF 213.90 (7%)

Details

A highly sensitive biomarker for the production of Aβ 1-42 derived from the βAPP-like protein APLP1. The peptide is generated by the same proteolytic mechanism as Aβ42. Non-amyloidogenic APL1β28 can be detected in the CSF and its levels correlate with Aβ42 production. Its ratio to total APL1β (APL1β25, APL1β27, and APL1β28) is significantly increased in familial and sporadic cases of AD.
Catalog Number H-7306
One Letter Code DELAPAGTGVSREAVSGLLIMGAGGGSL
Synonyms APLP1-derived Aβ-like peptide (1-28)
Molecular Formula C₁₀₉H₁₈₅N₃₁O₃₉S
Relative Molecular Mass 2585.92
CAS Registry Number 1233876-42-0
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Biomarker
Application Alzheimer's Disease
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Product citations

M.Okochi et al., Neurodegener. Dis., 7, 42 (2010)
K.Yanagida et al., EMBO Mol. Med., 1, 223 (2009)