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Details
An RGD tumor-targeting peptide, which binds to αvβ3 receptors. c(RGDfK) can be easily conjugated to fluorophore tags, chelators, or carriers. Palecek et al. converted the ε-amino group into the azide by diazo transfer allowing further functionalization by click chemistry. Mercapto groups can be introduced via acylation of c(RGDfK) with S-acetylthioacetic acid (SATA).
Catalog Number
H-7326
One Letter Code
c(RGDfK)
Synonyms
c(RGDfK)
Molecular Formula
C₂₇H₄₁N₉O₇
Relative Molecular Mass
603.68
CAS Registry Number
161552-03-0
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Links / Documents:
Bachem product citations
F.A.López-Durán et al.,
Bioquimia,
34,
61 (2009)
F.A.López-Durán et al.,
Bioquimia,
34,
61 (2009)
Product citations
J.Palecek et al,
Synthesis,
655 (2011)
R.Haubner et al.,
J. Am. Chem. Soc.,
118,
7461 (1996)