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Toxin GaTx1 trifluoroacetate salt
H-Cys-Gly-Pro-Cys-Phe-Thr-Thr-Asp-His-Gln-Met-Glu-Gln-Lys-Cys-Ala-Glu-Cys-Cys-Gly-Gly-Ile-Gly-Lys-Cys-Tyr-Gly-Pro-Gln-Cys-Leu-Cys-Asn-Arg-NH₂ trifluoroacetate salt (Disulfide bonds between Cys¹ and Cys¹⁸/Cys⁴ and Cys²⁵/Cys¹⁵ and Cys³⁰/Cys¹⁹ and Cys³²)


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price
4063634.0100 0.1 mg Request lead time  
CHF 255.00
CHF 237.15 (7%)


GaTx1 is a component of the venom of the yellow scorpion (Leiurus quinquestriatus hebraeus). The highly bridged 34-peptide, a chloride channel ligand, potently and reversibly inhibits cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels when the channels are in the interburst closed state. Since the toxin inhibits CFTR only when applied to the cytoplasmic side, it is unlikely that CFTR represents the native target. Manufactured and sold under license from Georgia Tech Research Corporation, USA; patent WO/2007/137163 (PCT/US2007/069243).
Catalog Number H-6678
Molecular Formula C₁₄₇H₂₂₄N₄₆O₄₇S₉
Relative Molecular Mass 3676.27
CAS Registry Number 1926163-15-6
Source Synthetic
Storage Conditions -20 ± 5 °C