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Details
The peptide hormone osteocalcin is involved not only in bone formation, it also plays an important role in glucose metabolism and could regulate testosteron. In mice, only the completely decarboxylated form of the peptide shows the latter hormonal activities, whereas in humans, osteocalcin, partially decarboxylated osteocalcins, and the uncarboxylated peptide seem to be involved. Generally, obese individuals have been shown to have lower osteocalcin(s) levels than non-obese controls, and type 2 diabetic individuals have lower plasma osteocalcin than non-diabetic individuals.
Catalog Number
H-7534
One Letter Code
YLYQWLGAPVPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV
Synonyms
Osteocalcin (1-49) (human) (decarboxylated)
Molecular Formula
C₂₆₆H₃₈₁N₆₇O₇₆S₂
Relative Molecular Mass
5797.49
CAS Registry Number
1927927-11-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Bone hormone involved in glucose metabolism
Application
Diabetes
Obesity Research
Obesity Research
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