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Details
Hexa-D-arginine amide is a potent furin inhibitor with a Ki of 0.106 μM. It also inhibited the related convertases PACE4 and prohormone convertase-1 (PC1) with Ki values of 0.58 μM and 13 μM, respectively. The stable hexapeptide exhibited protection against anthrax toxemia in vitro and in vivo.
Catalog Number
N-2000
One Letter Code
rrrrrr -NH₂
Synonyms
Hexa-D-arginine amide
Molecular Formula
C₃₆H₇₅N₂₅O₆
Relative Molecular Mass
954.16
CAS Registry Number
[673202-67-0] net
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Furin inhibitor
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4061351
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Furin |
