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4061351

Availability: In stock

Furin Inhibitor II trifluoroacetate salt
H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH₂ trifluoroacetate salt

4061351

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4061351.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 102.00
CHF 94.86 (7%)
4061351.0005 5 mg Ships within 3-5 business days  
CHF 408.00
CHF 379.44 (7%)

Details

Hexa-D-arginine amide is a potent furin inhibitor with a Ki of 0.106 μM. It also inhibited the related convertases PACE4 and prohormone convertase-1 (PC1) with Ki values of 0.58 μM and 13 μM, respectively. The stable hexapeptide exhibited protection against anthrax toxemia in vitro and in vivo.
Catalog Number N-2000
One Letter Code rrrrrr -NH₂
Synonyms Hexa-D-arginine amide
Molecular Formula C₃₆H₇₅N₂₅O₆
Relative Molecular Mass 954.16
CAS Registry Number [673202-67-0] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Furin inhibitor
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Product citations

M.S.Sarac et al., Infect. Immun., 72, 602 (2004)
A.Cameron et al., J. Biol. Chem., 275, 36741 (2000)

4061351

Enzyme Substrates Inhibitors
Furin