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Details
Virstatin represents a small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. By inhibiting the transcriptional regulator ToxT, it prevents expression of two critical V. cholerae virulence factors, cholera toxin and the toxin coregulated pilus. Orogastric administration of virstatin protects infant mice from intestinal colonization by V. cholerae.
Catalog Number
F-4195
Molecular Formula
C₁₆H₁₃NO₄
Relative Molecular Mass
283.28
CAS Registry Number
88909-96-0
Storage Conditions
-20 ± 5 °C
Keywords
Inhibitor of V.cholerae virulence
Application
Antimicrobial & Antiviral Peptides
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