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Details
Internally quenched substrate for calpain-1 (µ-calpain) with optimal cleavage motifs flanking the scissile bond. The enzyme showed a more than 18-fold higher turnover rate for the hydrolysis of this FRET substrate based on the amino acid sequence PLFAER than for EVYGMM a sequence derived from the cleavage site of the natural substrate α-spectrin.
Catalog Number
M-2655
Molecular Formula
C₇₂H₉₇N₁₇O₁₆S
Relative Molecular Mass
1488.73
CAS Registry Number
[1914987-47-5]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Calpain substrate
Areas of Interest
Alzheimer's Disease
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Product citations
4050532
Enzyme | Substrates | Inhibitors |
---|---|---|
Calpain |