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Availability: In stock

Apelin-17 (human, bovine, mouse, rat) trifluoroacetate salt

4050029

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4050029.0001 1 Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 232.00
CHF 215.76 (7%)
4050029.0005 5 Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 924.00
CHF 859.32 (7%)

Details

Apelin-17 is an endogenous ligand of the human orphan G protein-coupled receptor APJ, reported to act as a coreceptor of CD4 for human and simian immunodeficiency viruses. Apelin-17 and apelin-13 represent the predominant molecular forms of apelin present in the whole brain, hypothalamus, and plasma. Like apelin-13, apelin-17 exhibited a high activity on extracellular acidification rate and strongly inhibited forskolin-stimulated cAMP production in CHO cells expressing the human or the rat apelin receptor. The peptide might play a crucial role in the maintenance of body fluid homeostasis by counteracting AVP (arginine vasopressin) actions through inhibition of AVP neuron activity and AVP release.