Shopping Cart - CHF 0.00

You have no items in your shopping cart.

Return to Previous Page

Availability: Out of stock

(H-Asp-Glu-Val-Asp)₂-Rhodamine 110 trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price
4049432.0005 5 mg Request lead time  
CHF 189.00
CHF 175.77 (7%)


(DEVD)₂-R110, non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide, is a highly sensitive, photostable fluorogenic substrate for the determination of caspase-3 activity. Characteristic for substrates based on Rhodamine 110 (R110) is that they contain two identical amino acids or peptides attached to a single fluorophor thereby suppressing its visible absorption and its fluorescence. Upon enzymatic cleavage, this substrate is converted first to the fluorescent monoamide and then to the even more fluorescent R110. The spectral properties of these hydrolysis products are similar to those of fluorescein, with peak excitation and emission wavelengths of 496 and 520 nm, respectively. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy. Useful for high throughput screening applications.
Catalog Number M-2620
APC Number 81-6-67
Synonyms (Asp-Glu-Val-Asp)2-Rhodamine 110, (DEVD)₂-R110
Molecular Formula C₅₆H₆₆N₁₀O₂₃
Relative Molecular Mass 1247.19
CAS Registry Number 220846-75-3
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Caspase-3 substrate
Application Apoptosis & Necrosis


Enzyme Substrates Inhibitors
"Caspase-3 (CPP-32; Yama; Apopain)"