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Details
Highly potent and selective β-MSH-derived melanocortin-4 receptor (MC-4R) agonist with sub-nanomolar potency. The binding affinities for human MC-4R, MC-1R, MC-3R and MC-5R were 0.55 ± 0.06, 16.78 ± 1.53, 56.79 ± 4.66, and < 500 nM, respectively. Daily subcutaneous injection of H-6268 to diet-induced obese rats over a period of 14 days demonstrated an effect on reduction of fat mass.
Catalog Number
H-6268
One Letter Code
Ac-rCEHfRWC-NH₂
Molecular Formula
C₅₁H₇₀N₁₈O₁₁S₂
Relative Molecular Mass
1175.36
CAS Registry Number
819048-44-7
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Obesity Research
Pituitary & Hypothalamic Hormones
Pituitary & Hypothalamic Hormones
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