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4049312

Availability: In stock

Acetyl-(D-Arg¹⁰,Cys¹¹,D-Phe¹⁴,Cys¹⁷)-β-MSH (10-17) amide trifluoroacetate salt
Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH₂ trifluoroacetate salt
(Disulfide bond)

4049312

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4049312.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 126.00
CHF 117.18 (7%)
4049312.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 504.00
CHF 468.72 (7%)
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Details

Highly potent and selective β-MSH-derived melanocortin-4 receptor (MC-4R) agonist with sub-nanomolar potency. The binding affinities for human MC-4R, MC-1R, MC-3R and MC-5R were 0.55 ± 0.06, 16.78 ± 1.53, 56.79 ± 4.66, and < 500 nM, respectively. Daily subcutaneous injection of H-6268 to diet-induced obese rats over a period of 14 days demonstrated an effect on reduction of fat mass.
Catalog Number H-6268
One Letter Code Ac-rCEHfRWC-NH₂
Molecular Formula C₅₁H₇₀N₁₈O₁₁S₂
Relative Molecular Mass 1175.36
CAS Registry Number [819048-44-7] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Obesity Research
Pituitary & Hypothalamic Hormones
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Bachem product citations

S.Veiksina et al., Biochim. Biophys. Acta, 1838, 372 (2014)

Product citations

J.P.Mayer et al., J. Med. Chem., 48, 3095 (2005)