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4049308

Availability: In stock

Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH

4049308

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4049308.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 158.00
CHF 146.94 (7%)
4049308.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 630.00
CHF 585.90 (7%)

Details

Abz-GIVRAK(Dnp), a very efficient and selective FRET substrate for human cathepsin B (Km = 5.9 µM, kcat = 43 s⁻¹, kcat/Km = 7288 mM⁻¹s⁻¹). The kcat/Km values for cathepsin K, L, V, X, and cruzain were 133.3, 100, 32, 17, and 75 mM⁻¹s⁻¹, respectively.
Catalog Number M-2595
Molecular Formula C₄₁H₆₁N₁₃O₁₂
Relative Molecular Mass 928.02
CAS Registry Number 827044-38-2
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Cathepsin B FRET substrate
Application Alzheimer's Disease
Links / Documents:

Bachem product citations

M.Lopez-Pelegrin et al., Angew. Chem. Int. Ed. Engl., 53, 10624 (2014)
M.Lopez-Pelegrin et al., Angew. Chem. Int. Ed. Engl., 53, 10624 (2014)
M.Lopez-Pelegrin et al., J. Biol. Chem., 288, 21279 (2013)
B.Mirkovic et al., FEBS J., 276, 4739 (2009)

Product citations

S.S.Cotrin et al., Anal. Biochem., 335, 244 (2004)

4049308

Enzyme Substrates Inhibitors
Cathepsin B    
Cruzipain