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Promobanner OCT 2020

Availability: In stock

Z-Ile-Leu-aldehyde

4048245

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4048245.0005 5 mg Ships within 3-5 business days  
CHF 210.00
CHF 195.30 (7%)

Details

Z-IL-CHO, a cell-permeable, reversible inhibitor, reduces amyloid β (Aβ)-production by blocking γ-secretase activity in vitro (Aβ₄₀ IC₅₀ = 7.9 µM; Aβ₄₂ IC₅₀ = 7.6 µM). Besides blocking the formation of Aβ the dipeptide aldehyde Z-IL-CHO also blocks the production of the γ-CTF (γ-secretase-generated carboxyl-terminal fragment), but does not affect the formation of amyloid-β-precursor protein (APP).
Catalog Number N-1895
Molecular Formula C₂₀H₃₀N₂O₄
Relative Molecular Mass 362.47
CAS Registry Number 161710-10-7
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Alzheimer's Disease

4048245

Enzyme Substrates Inhibitors
γ-Secretase