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H-Glu-Leu-Asp-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]-Val-Glu-Phe-Gly-Gly-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-OH trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4047413.0500 0.5 mg Ships within 3-5 business days  
CHF 683.00
CHF 635.19 (7%)
4047413.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,156.00
CHF 1,075.08 (7%)


A memapsin-2 (β-secretase) inhibitor consisting of the transition-state inhibitor of memapsin-2, OM00-3, (Ki = 0.31 nM) covalently linked to a nine-residue poly D-arginine carrier protein. [OM00-3]r₉ (ELDLpsi[CHOH-CH₂]AVEFGGr₉) was shown to penetrate the plasma membrane of cultured cells and to inhibit production of amyloid β-protein. In transgenic Tg2576 mice with amyloid plaque pathology intraperitoneal injection of N-1920 resulted in a significant decrease in amyloid β-protein levels in plasma and brain.
Catalog Number N-1920
Synonyms [OM00-3]r₉, [OM00-3]DR₉
Molecular Formula C₁₀₂H₁₈₃N₄₅O₂₆
Relative Molecular Mass 2455.86
CAS Registry Number 527674-72-2
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease


Enzyme Substrates Inhibitors