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Details
Galanin-like peptide (GALP) is a 60 amino acid neuropeptide first isolated from the porcine hypothalamus and subsequently also identified in rats and humans. GALP exhibits a higher affinity (~18-fold) for the GALR2 receptor compared to the GALR1 receptor, whereas galanin is relatively non-selective. Investigations of the physiological role of GALP revealed that GALP induces food intake with a ten times higher orexigenic activity than galanin. Furthermore, GALP could affect the emotional state in the CNS. Therefore, GALP represents an orexigenic and anxiogenic peptide.
Catalog Number
H-6078
One Letter Code
APAHRGRGGWTLNSAGYLLGPVLHLPQMGDQDGKRETALEILDLWKAIDGLPYSHPPQPS
Synonyms
GALP (human)
Molecular Formula
C₂₉₂H₄₅₁N₈₃O₈₄S
Relative Molecular Mass
6500.37
CAS Registry Number
245114-99-2
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Obesity Research
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