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Availability: In stock

Calpain Inhibitor VI


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4043024.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 189.00
CHF 175.77 (7%)
4043024.0005 5 mg Ships within 3-5 business days  
CHF 757.00
CHF 704.01 (7%)


4-Fluorobenzenesulfonyl-VL-CHO is a potent inhibitor of calpain I and II (IC₅₀ = 7.5 nM and 78 nM, respectively) but also of cathepsin B (IC₅₀ = 15 nM) and cathepsin L (IC₅₀ = 1.5 nM). The IC₅₀ values for other proteases such as interleukin 1β-converting enzyme, thrombin, factor VIIa, trypsin and chymotrypsin were above 100 µM.
Catalog Number N-1855
Synonyms SJA6017, 4-Fluoro-benzenesulfonyl-Val-L-leucinal
Molecular Formula C₁₇H₂₅FN₂O₄S
Relative Molecular Mass 372.46
CAS Registry Number 190274-53-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Calpain and cathepsin inhibitor


Enzyme Substrates Inhibitors
Cathepsin L    
Cathepsin B