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4043013

Availability: In stock

Dnp-(Leu⁴²¹)-Collagen Type VIII α1 Chain (419-426) amide (human, mouse) trifluoroacetate salt
Dnp-Gly-Pro-Leu-Gly-Met-Arg-Gly-Leu-NH₂ trifluoroacetate salt

4043013

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4043013.0001 1 mg Ships within 3-5 business days  
CHF 73.00
CHF 67.89 (7%)
4043013.0005 5 mg Ships within 3-5 business days  
CHF 294.00
CHF 273.42 (7%)
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Details

Highly sensitive and selective substrate for collagenase-3 (MMP-13) with a kcat/Km value of 4.22 · 10⁶ M⁻¹s⁻¹ (pH = 7.5, T = 37 °C). The kcat/Km value of human collagenase-3 for this synthetic peptide is 1344-, 11-, and 820-fold better than that of related MMPs stromelysin-1 (MMP-3), gelatinase B (MMP-9), and collagenase-1 (MMP-1), respectively.
Catalog Number M-2530
APC Number 76-4-83
One Letter Code Dnp-GPLGMRGL-NH₂
Synonyms MMP-13, Substrate
Molecular Formula C₄₀H₆₄N₁₄O₁₂S
Relative Molecular Mass 965.10
CAS Registry Number [1872435-02-3] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Cancer Research
Inflammation Research
Links / Documents:
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Product citations

S.-J.Deng et al., J. Biol. Chem., 275, 31422 (2000)

4043013

Enzyme Substrates Inhibitors
Collagenase-3    
Matrix Metalloproteinase-13 (MMP-13)