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4040959

Availability: In stock

Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH₂ trifluoroacetate salt

4040959

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4040959.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 252.00
CHF 234.36 (7%)

Details

Among the fluorescent peptide substrates analyzed, the FRET substrate Mca-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH₂ displayed the highest specificity constant with MMP-26 (kcat/Km = 3.0 · 10⁴ M⁻¹s⁻¹, pH 7.5, T = 25 °C). The fluorescence was measured at an excitation wavelength of 328 nm and emission wavelength of 393 nm.
Catalog Number M-2520
APC Number 76-4-85
One Letter Code Mca-PLA-Nva-Dpa-AR-NH₂
Synonyms MMP-2 Substrate, Fluorogenic
Molecular Formula C₄₉H₆₈N₁₄O₁₅
Relative Molecular Mass 1093.16
CAS Registry Number 256394-92-0
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Inflammation Research
Links / Documents:

Bachem product citations

S.Fridrich et al., Curr. Protoc. Protein Sci., 83, (2016)
C.De Savi et al., Bioorg. Med. Chem. Lett., 21, 1376 (2011)
C.De Savi et al., Bioorg. Med. Chem. Lett., 21, 4215 (2011)
L.Howard et al., FEBS Lett., 498, 82 (2001)

Product citations

H.I.Park et al., J. Biol. Chem., 277, 35168 (2002)
L.Howard et al., FEBS Lett., 498, 82 (2001)
V.Knäuper et al., Eur. J. Biochem., 268, 1888 (2001)

4040959

Enzyme Substrates Inhibitors
Matrix Metalloproteinase-26 (MMP-26)