Shopping Cart - CHF 0.00

You have no items in your shopping cart.

Return to Previous Page

Availability: In stock

Hepcidin-25 (human) trifluoroacetate salt
H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt (Disulfide bonds between Cys⁷ and Cys²³/Cys¹⁰ and Cys¹³/Cys¹¹ and Cys¹⁹/Cys¹⁴ and Cys²²)


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4040671.0100 0.1 mg Ships within 3-5 business days  
CHF 204.00
CHF 189.72 (7%)
4040671.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 630.00
CHF 585.90 (7%)
4040671.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 999.00
CHF 929.07 (7%)


Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. Hepcidin acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity. Former CAS-number 342790-21-0.
Catalog Number H-5926
APC Number 87-9-65
Synonyms Liver-Expressed Antimicrobial Peptide (human), LEAP-1 (human), Hepc25 (human), PLTR (human), Putative Liver Tumor Regressor (human)
Molecular Formula C₁₁₃H₁₇₀N₃₄O₃₁S₉
Relative Molecular Mass 2789.40
CAS Registry Number 1356390-47-0
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Principal iron-regulatory hormone; Antimicrobial peptide