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Details
The Flemish mutation (A21G) shows a decreased tendency to aggregate and a reduced neurotoxicity. A21G is pathogenic as it is degraded significantly more slowly by neprilysin than WT Abeta42.
Catalog Number
H-7846
One Letter Code
DAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVVIA
Synonyms
Amyloid-beta Protein (1-42) (human), Flemish Mutation, Amyloid β-Protein (1-42) Flemish Mutation, [Gly21]-Abeta (1-42), Human, Amyloid-beta Peptide (1-42), A21G, Human, Amyloid β-Protein (1-42) A21G, [Gly21] - beta - Amyloid (1 - 42)
Molecular Formula
C₂₀₂H₃₀₉N₅₅O₆₀S
Relative Molecular Mass
4500.08
CAS Registry Number
4039930
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Alzheimer's Disease
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