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4039188

Availability: In stock

(Hyp⁴⁷⁴·⁴⁷⁷,Gln⁴⁷⁹)-cyclo-α-Fetoprotein (471-479) (human, lowland gorilla)
Cyclo(-Glu-Met-Thr-Hyp-Val-Asn-Hyp-Gly-Gln)

4039188

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4039188.0005 5 mg Ships within 3-5 business days  
CHF 1,429.00
CHF 1,328.97 (7%)

Details

The cyclic α-fetoprotein-derived peptide analog efficiently inhibited the growth of estrogen-dependent MCF-7 human breast cancer cell xenografts. The extent of inhibition was similar to that of tamoxifen. In contrast to tamoxifen the peptide did not interfere with estrogen binding to its receptor and therefore further development of this compound might yield a new class of valuable agents for the effective treatment of breast cancer.
Catalog Number H-5652
Synonyms (Hyp⁴⁷⁴·⁴⁷⁷,Gln⁴⁷⁹)-cyclo-α-Fetoglobulin (471-479) (human, lowland gorilla)
Molecular Formula C₄₀H₆₃N₁₁O₁₆S
Relative Molecular Mass 986.07
CAS Registry Number 393827-70-8
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Cancer Research
Links / Documents:

Product citations

F.B.Mesfin et al., J. Pept. Res., 58, 246 (2001)