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Details
The cyclic α-fetoprotein-derived peptide analog efficiently inhibited the growth of estrogen-dependent MCF-7 human breast cancer cell xenografts. The extent of inhibition was similar to that of tamoxifen. In contrast to tamoxifen the peptide did not interfere with estrogen binding to its receptor and therefore further development of this compound might yield a new class of valuable agents for the effective treatment of breast cancer.
Catalog Number
H-5652
Synonyms
(Hyp⁴⁷⁴·⁴⁷⁷,Gln⁴⁷⁹)-cyclo-α-Fetoglobulin (471-479) (human, lowland gorilla)
Molecular Formula
C₄₀H₆₃N₁₁O₁₆S
Relative Molecular Mass
986.07
CAS Registry Number
393827-70-8
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Cancer Research
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