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4038214

Availability: In stock

TRH
Pyr-His-Pro-NH₂

4038214

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4038214.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)
4038214.1000 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 630.00
CHF 585.90 (7%)
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Details

TRH exhibits a variety of biological effects, when injected into humans or animals. Its physiological role appears to be the stimulation of thyrotropin (TSH) and prolactin (PRL) release from the anterior pituitary. Though it was first identified in the hypothalamus as a regulator of the pituitary-thyroid axis, TRH was detected as well by Luo et al. in pancreatic β-cells co-localized with insulin. Application of the hormone reverted hyperglycemia in rats. Moreover, TRH plays an important role in the control of human hair-growth and hair follicle pigmentation.
Catalog Number H-4915
APC Number 52-0-80
One Letter Code pEHP-NH₂
Synonyms Thyroliberin, Prolactoliberin, Prolactostatin, Protirelin, Thyrotropin-Releasing Hormone
Molecular Formula C₁₆H₂₂N₆O₄
Relative Molecular Mass 362.39
CAS Registry Number [24305-27-9]
EINECS Number 246-143-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Di- and Tripeptides
Diabetes
Obesity Research
Veterinary Medicine
Links / Documents:
Brochures:

Bachem product citations

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Product citations

E.Gaspar et al., J. Invest. Dermatol., 131, 2368 (2011)
E.Gaspar et al., FASEB J., 24, 393 (2010)
L.Luo et al., Biochem. Biophys. Res. Commun., 374, 69 (2008)
G.G.Yarbrough et al., Med. Hypotheses, 69, 1249 (2007)
L.Luo and N.Yano, Endocr. Res., 31, 185 (2005)
Y.H.Choi et al., Physiol. Behav., 77, 1 (2002)
H.Heuer et al., Acta Med. Austriaca, 26, 119 (1999)
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