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Details
TRH exhibits a variety of biological effects, when injected into humans or animals. Its physiological role appears to be the stimulation of thyrotropin (TSH) and prolactin (PRL) release from the anterior pituitary. Though it was first identified in the hypothalamus as a regulator of the pituitary-thyroid axis, TRH was detected as well by Luo et al. in pancreatic β-cells co-localized with insulin. Application of the hormone reverted hyperglycemia in rats. Moreover, TRH plays an important role in the control of human hair-growth and hair follicle pigmentation.
Catalog Number
H-4915
APC Number
52-0-80
One Letter Code
pEHP-NH₂
Synonyms
Thyroliberin, Protirelin, Prolactoliberin, Prolactostatin, Thyrotropin-Releasing Hormone
Molecular Formula
C₁₆H₂₂N₆O₄
Relative Molecular Mass
362.39
CAS Registry Number
24305-27-9
EINECS Number
246-143-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
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