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Details
pEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV, the N-terminally truncated isoform of the amyloid β-protein (Aβ) beginning with a pyroglutamate (Pyr) residue at position 11 was used in experiments studying the generality of fibrillogenesis-related helix formation. Comparing the fibrillogenesis kinetics of many of the most important clinically relevant amyloid β-protein alloforms it could be observed that among these peptides (Pyr¹¹)-amyloid β-protein (11-40) exhibited the greatest retardation of fibrillization rate.
Catalog Number
H-6382
One Letter Code
pEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Molecular Formula
C₁₄₃H₂₂₆N₃₈O₃₉S
Relative Molecular Mass
3133.67
CAS Registry Number
192377-94-9
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Alzheimer's Disease
Links / Documents:
Bachem product citations
K.Tanabe et al.,
Chemical Science,
5,
2747 (2014)
