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Details
H-Pro-Gly-Pro-OH (PGP) is a tripeptide generated from the breakdown of extracellular matrix collagen and is specifically chemotactic for neutrophils in vitro and in vivo. N-terminal acetylation of PGP (AcPGP - Bachem product H-6412) can enhance this chemotactic potential. PGP was identified as physiological substrate for the aminopeptidase activity of leukotriene A4 hydrolase. PGP is a biomarker for chronic obstructive pulmonary disease (COPD).
Catalog Number
H-7284
One Letter Code
PGP
Molecular Formula
C₁₂H₁₉N₃O₄
Relative Molecular Mass
269.30
CAS Registry Number
[7561-51-5]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
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