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Details
Protease-activated receptor-4 activating peptide derived from murine PAR-4. GYPGKF-amide was able to cause rat platelet aggregation with an EC₅₀ value of 40 µM. Its effect on leucocyte rolling and adherence points at a role of PAR-4 in mediating proinflammatory processes.
Catalog Number
H-6054
APC Number
85-2-07
One Letter Code
GYPGKF-NH₂
Synonyms
Proteinase Activated Receptor 4 (1-6) amide (mouse), GYPGKFamide, Thrombin Receptor-Like 3 (1-6) amide (mouse), Coagulation Factor II Receptor-Like 3 (1-6) amide (mouse), GYPGKF-NH2 Selective Protease-Activated Receptor 4 (PAR4) Agonist
Molecular Formula
C₃₃H₄₆N₈O₇
Relative Molecular Mass
666.78
CAS Registry Number
245443-52-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
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