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4034828

Availability: In stock

(D-Phe¹¹,His¹²)-Sauvagine (11-40) trifluoroacetate salt
H-D-Phe-His-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH₂ trifluoroacetate salt

4034828

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4034828.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 384.00
CHF 357.12 (7%)

Details

ASV-30, a conformationally constrained analog of sauvagine, is a highly potent and selective antagonist directed against mouse CRF receptor type 2β (mCRFR2β). It has been shown to suppress agonist-induced adenylate cyclase activity in human embryonic kidney (HEK) 293 cells expressing mCRFR2β.
Catalog Number H-5844
APC Number 34-7-12
One Letter Code fHLLRKMIEIEKQEKEKQQAANNRLLLDTI-NH₂
Synonyms Antisauvagine-30
Molecular Formula C₁₆₁H₂₇₄N₄₈O₄₆S
Relative Molecular Mass 3650.31
CAS Registry Number 220673-95-0
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Cardiovascular System & Diseases
Links / Documents:

Bachem product citations

T.Fenzl et al., Behav. Brain Res., 222, 43 (2011)
E.Gutknecht et al., J. Neurochem., 104, 926 (2008)
E.Gutknecht et al., J. Neurochem., 104, 926 (2008)

Product citations

A.Rühmann et al., Proc. Natl. Acad. Sci. USA, 95, 15264 (1998)