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Details
Orthogonally protected derivative of homocysteic acid. As a Glu substitute, or for introducing a highly acidic moiety, it can be incorporated into various peptide effectors, such as receptor ligands and enzyme inhibitors. The neopentyl sulfonate can be cleaved with HF/m-cresol or by slow hydrolysis in 0.1% TFA in water/acetonitrile. This cysteic acid homolog occurs in nature; homocysteic acid, generated from plasma homocysteine, can damage endothelial tissue.
Catalog Number
F-4040
Molecular Formula
C₂₄H₂₉NO₇S
Relative Molecular Mass
475.56
CAS Registry Number
220951-81-5
Storage Conditions
+5 ± 3 °C
Links / Documents:
Product citations
L.Bischoff et al.,
J. Org. Chem.,
64,
1420 (1999)
