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4034611

Availability: In stock

Z-Leu-Arg-AMC hydrochloride salt

4034611

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4034611.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 368.00
CHF 342.24 (7%)
4034611.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,471.00
CHF 1,368.03 (7%)
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Details

Z-LR-AMC, a fluorogenic substrate for cathepsin L, S, and V, human tissue kallikrein, and the falcipains I - III. Z-LR-AMC is the preferred substrate of falcipain II, a hemoglobin-degrading cysteine protease from Plasmodium falciparum, one of the most promising targets for antimalarial drug design. Z-LR-AMC is used for assaying cathepsin K, an enzyme involved in osteoclastic bone resorption.
Catalog Number I-1960
One Letter Code Z-LR-AMC
Molecular Formula C₃₀H₃₈N₆O₆
Relative Molecular Mass 578.67
CAS Registry Number [156192-32-4] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Osteoporosis Research
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Bachem product citations

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Product citations

A.Singh et al., Protein Eng. Des. Sel., 20, 171 (2007)
T.Cheng et al., J. Biol. Chem., 281, 15893 (2006)
M.Debela et al., J. Biol. Chem., 281, 25678 (2006)
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P.S.Sijwali and P.J.Rosenthal, Proc. Natl. Acad. Sci. USA, 101, 4384 (2004)
P.S.Sijwali et al., Biochem. J., 360, 481 (2001)

4034611

Enzyme Substrates Inhibitors
Tissue Kallikrein    
Cathepsin S    
Cathepsin L    
Falcipain I    
Falcipain II    
Cathepsin K    
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