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4034611

Availability: In stock

Z-Leu-Arg-AMC hydrochloride salt

4034611

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4034611.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 368.00
CHF 342.24 (7%)
4034611.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,471.00
CHF 1,368.03 (7%)
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Details

Z-LR-AMC, a fluorogenic substrate for cathepsin L, S, and V, human tissue kallikrein, and the falcipains I - III. Z-LR-AMC is the preferred substrate of falcipain II, a hemoglobin-degrading cysteine protease from Plasmodium falciparum, one of the most promising targets for antimalarial drug design. Z-LR-AMC is used for assaying cathepsin K, an enzyme involved in osteoclastic bone resorption.
Catalog Number I-1960
One Letter Code Z-LR-AMC
Molecular Formula C₃₀H₃₈N₆O₆
Relative Molecular Mass 578.67
CAS Registry Number [156192-32-4] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Osteoporosis Research
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Bachem product citations

M.Paireder et al., Arch. Biochem. Biophys., 603, 110 (2016)
M.Klemencic et al., Mol. Microbiol., 98, 142 (2015)
L.Z.Swisher et al., Biosens. Bioelectron., 56, 129 (2014)
L.Z.Swisher et al., J. Phys. Chem. C. Nanomater. Interfaces, 117, 4268 (2013)
H.Huang et al., Bioorg. Med. Chem. Lett., 22, 958 (2012)
T.M.Martins et al., Acta Trop., 121, 1 (2012)
M.W.Robinson et al., PLoS Negl. Trop. Dis., 5, e1012 (2012)
M.Frizler et al., J. Med. Chem., 54, 396 (2011)
A.Breuning et al., J. Med. Chem., 53, 1951 (2010)
M.J.Leyva et al., Chem. Biol., 17, 1189 (2010)
Y.M.Ohol et al., Cell Host Microbe, 7, 210 (2010)
R.L.Caldeira et al., Exp. Parasitol., 122, 97 (2009)
J.Zhu et al., Molecules, 14, 494 (2009)
C.M.Stack et al., J. Biol. Chem., 283, 9896 (2008)
F.Schulz et al., ChemMedChem, 2, 1214 (2007)
A.Singh et al., Protein Eng. Des. Sel., 20, 171 (2007)
K.C.Pandey et al., PLoS Pathog., 2, e117 (2006)
A.W.Patterson et al., J. Med. Chem., 49, 6298 (2006)
R.Loser et al., J. Med. Chem., 48, 7688 (2005)

Product citations

A.Singh et al., Protein Eng. Des. Sel., 20, 171 (2007)
T.Cheng et al., J. Biol. Chem., 281, 15893 (2006)
M.Debela et al., J. Biol. Chem., 281, 25678 (2006)
N.Micale et al., J. Med. Chem., 49, 3064 (2006)
C.Serveau-Avesque et al., Biol. Cell, 98, 15 (2006)
P.S.Sijwali and P.J.Rosenthal, Proc. Natl. Acad. Sci. USA, 101, 4384 (2004)
P.S.Sijwali et al., Biochem. J., 360, 481 (2001)

4034611

Enzyme Substrates Inhibitors
Tissue Kallikrein    
Cathepsin S    
Cathepsin L    
Falcipain I    
Falcipain II    
Cathepsin K    
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