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Details
BQ-610 is a very potent ET-A receptor antagonist which is about 30000 times more selective for ET-A receptors than for ET-B receptors. Furthermore, it has been found that BQ-610 strongly antagonizes ET-1 induced concentration in porcine coronary artery with a pA₂ value of 8.2.
Catalog Number
H-4914
APC Number
88-2-32
Molecular Formula
C₃₆H₄₄N₆O₆
Relative Molecular Mass
656.78
CAS Registry Number
141595-53-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Endothelin antagonist. BQ610 binds to the ET-A receptor with IC₅₀ 20 nM.
Application
Cardiovascular System & Diseases
Links / Documents:
Bachem product citations
Product citations
K.Ishikawa et al.,
Peptides 1992, Proceedings of the 22nd European Peptide Symposium, Interlaken, Switzerland, p. 685, C.H.Schneider and A.N.Eberle, eds., Escom, Leiden,
(1993)