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Details
This adrenomedullin fragment possessed vasodilatory activity. It has been suggested to modulate receptor-mediated, but not voltage-dependent, pulmonary vascular contraction by influencing Ca²⁺ influx. Therefore, it has been proposed that hADM (13-52) acts as an endothelium-dependent vasodilator agent in the pulmonary vascular bed of the rat. Furthermore, this compound may act as a modulator of the vascular phases of inflammation.
Catalog Number
H-4936
APC Number
22-1-11
One Letter Code
SFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH₂
Molecular Formula
C₂₀₀H₃₀₈N₅₈O₅₉S₂
Relative Molecular Mass
4533.13
CAS Registry Number
[154765-05-6]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Cardiovascular System & Diseases
Inflammation Research
Inflammation Research
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