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Details
This anti-opiate neuropeptide has been implicated in pain modulation as well as in opioid tolerance and may play a critical role in this process. For the neuropeptide Y-like human orphan G protein-coupled receptor HLWAR77 this peptide exhibited an EC₅₀ value of 1.26 nM. Furthermore, it has been shown to modulate a variety of physiological processes such as food intake, insulin release, blood pressure regulation and electrolyte balance. Please see also also our anorexigenic Y₁ receptor ligand BIBP3226 (E-3620).
Catalog Number
H-4946
One Letter Code
AGEGLNSQFWSLAAPQRF-NH₂
Synonyms
A-18-F-amide (human), NPAF (human)
Molecular Formula
C₉₀H₁₃₂N₂₆O₂₅
Relative Molecular Mass
1978.20
CAS Registry Number
[192387-38-5] net
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Opioid Research
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