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Details
Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. p3 is a major constituent of diffuse plaques observed in AD brains and pre-amyloid plaques in people affected by Down syndrome.
Catalog Number
H-7532
APC Number
62-0-85
One Letter Code
LVFFAEDVGSNKGAIIGLMVGGVV
Synonyms
β-Amyloid (17-40)
Molecular Formula
C₁₁₀H₁₇₈N₂₆O₃₁S
Relative Molecular Mass
2392.85
CAS Registry Number
156790-69-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
p3 Peptide
Application
Alzheimer's Disease
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