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Details
Human ghrelin (GHR), the endogenous ligand of the growth hormone secretagogue receptor (GHS-R), potently stimulates GH release. The Ser³ octanoyl ester turned out to be essential for generating this activity. Ghrelin plays an important role in the short-time regulation of appetite and in the long-time regulation of energy balance and glucose homeostasis.
A number of studies showed that ghrelin is also involved in the regulation of gastrointestinal, cardiovascular, and immune functions as well as in bone metabolism.
Catalog Number
H-4864
APC Number
55-0-02
Molecular Formula
C₁₄₉H₂₄₉N₄₇O₄₂
Relative Molecular Mass
3370.91
CAS Registry Number
258279-04-8
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Orexigenic hormone
Application
Diabetes
Obesity Research
Obesity Research
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