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4033017

Availability: In stock

Glucagon (1-29) (human, rat, porcine)
H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH

4033017

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4033017.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)
4033017.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 840.00
CHF 781.20 (7%)

Details

Glucagon is a 29 amino acid containing peptide hormone processed from proglucagon. As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo in both animals and humans. Not surprisingly, glucagon and glucagon receptor have been pursued extensively as potential targets for the therapeutic treatment of diabetes. As Aβ peptides and IAPP, glucacon tends to form gel-like fibrillar aggregates. These fibrils were found to be toxic through the activation of apoptotic signaling pathways. Hence the aggregation behavior of glucagon has been studied extensively.
Catalog Number H-6790
One Letter Code HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
Synonyms Glucagon, human
Molecular Formula C₁₅₃H₂₂₅N₄₃O₄₉S
Relative Molecular Mass 3482.80
CAS Registry Number 16941-32-5
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Diabetes
Veterinary Medicine
Links / Documents:
Brochures:

Bachem product citations

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Product citations

J.A.Harney and R.L.Rogers, Am. J. Physiol. Endocrinol. Metab., 295, E155 (2008)
P.A.Christensen et al., FEBS Lett., 582, 1341 (2008)
J.S.Pedersen et al., Biochemistry, 45, 14503 (2006)
S.Onoue et al., J. Chromatogr. A, 1109, 167 (2006)
G.Jiang and B.B.Zhang, Am. J. Physiol. Endocrinol. Metab., 284, E671 (2003)
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