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Availability: In stock

PyBOP
Benzotriazol-1-yloxy-tripyrrolidino-phosphonium hexafluorophosphate

4031604

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4031604.0025 25 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 168.00
CHF 156.24 (7%)
4031604.0100 100 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 504.00
CHF 468.72 (7%)
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Details

A trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a well-established, effective coupling reagent. It has been developed to replace BOP which generates the carcinogenic HMPT as a by-product during coupling. Contrary to activation with uronium/aminium-type coupling reagents, by-products resulting from guanidinylation of the amino group cannot be formed. PyBOP has been used as well for obtaining peptide thioesters.
Catalog Number Q-2715
Molecular Formula C₁₈H₂₈N₆OP · PF₆
Relative Molecular Mass 520.40
CAS Registry Number [128625-52-5]
Storage Conditions +5 ± 3 °C

Product citations

R.von Eggelkraut-Gottanka et al., Tetrahedron Lett., 44, 3551 (2002)
J.Coste et al., Tetrahedron Lett., 31, 205 (1990)