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Details
VIP antagonist, a hybrid of neurotensin (6-11) and VIP (7-28), is a competitive antagonist of VIP-binding to glial cells. In rats with reduced masculine potential, The peptide markedly inhibits VIP-stimulated sexual behaviour. Furthermore, it has been shown to antagonize VIP receptors on non-small cell lung cancer cells, thereby inhibiting tumor growth in vitro and in vivo.
Catalog Number
H-9935
APC Number
48-6-31
One Letter Code
KPRRPYTDNYTRLRKQMAVKKYLNSILN-NH₂
Synonyms
[Lys1, Pro2,5, Arg3,4, Tyr6] VIP, human, porcine, rat, ovine
Molecular Formula
C₁₅₄H₂₅₇N₄₉O₄₀S
Relative Molecular Mass
3467.11
CAS Registry Number
125093-93-8
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Cancer Research
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