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Details
The peptide T1, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. T1 has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor.
MSRPACPNDKYE has served as model peptide in protein modification and MS studies.
MSRPACPNDKYE has served as model peptide in protein modification and MS studies.
Catalog Number
H-2514
One Letter Code
MSRPACPNDKYE
Synonyms
T1
Molecular Formula
C₅₈H₉₁N₁₇O₂₀S₂
Relative Molecular Mass
1410.60
CAS Registry Number
[207553-92-2]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Cardiovascular System & Diseases
Hematology
Hematology
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