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Details
The peptide T1, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. T1 has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor.
MSRPACPNDKYE has served as model peptide in protein modification and MS studies.
Catalog Number
H-2514
One Letter Code
MSRPACPNDKYE
Synonyms
T1
Molecular Formula
C₅₈H₉₁N₁₇O₂₀S₂
Relative Molecular Mass
1410.60
CAS Registry Number
207553-92-2
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Cardiovascular System & Diseases
Hematology
Hematology
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