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(Dap²²)-Stichodactyla helianthus Neurotoxin (ShK)
H-Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Dap-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys-OH (Disulfide bonds between Cys³ and Cys³⁵/Cys¹² and Cys²⁸/Cys¹⁷ and Cys³²)


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4031226.0500 0.5 mg Ships within 3-5 business days  
CHF 2,123.00
CHF 1,974.39 (7%)
4031226.1000 1 mg Ships within 3-5 business days  
CHF 3,814.00
CHF 3,547.02 (7%)


This derivative of H-2358 is a very potent Kv 1.3 channel specific immunosuppressive peptide (Kd = 20 pM). It inhibited T cell proliferation.
Catalog Number H-4218
Synonyms (Dap ²²)-ShK
Molecular Formula C₁₆₆H₂₆₈N₅₄O₄₈S₇
Relative Molecular Mass 4012.75
CAS Registry Number 220384-25-8
Source Synthetic
Storage Conditions -20 ± 5 °C